Pierre de Fermat's world (c. 1605–1665) abounds in results in number theory, many of them concerning Diophantine equations.
A range of questions in number theory --------------------------------------
"There is no number one less than a multiple of 3 that is the sum of a square and three times another square."
"There is no right triangle with integer sides whose area is a square number."
"No cube can be expressed as the sum of two cubes."